A Trial of SHR-3792 Injection in Patients With Advanced Solid Tumors

Recruiting now · Phase 1

Conditions studied: Advanced Solid Tumors

In brief

The study is being conducted to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of SHR-3792 injection monotherapy for patients with advanced solid tumors, and to explore the reasonable dosage of SHR-3792 injection monotherapy for patients with advanced solid tumors.

Key facts

Study ID

NCT06907628

Run by

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

People needed

150

Starts

2025-04-02

Expected to finish

2027-02-01

Last updated by the study team

2025-04-25

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects with ability to understand and voluntarily agree to participate by giving written informed consent form for the study.
• Patients with unresectable recurrent or metastatic solid tumors.
• There is at least one lesion that could be measured.
• An Eastern Cooperative Oncology Group (ECOG) performance status (PS) score of 0 or 1.
• Adequate organ functions as defined.
• Life expectancy ≥ 3 months.

You may not qualify if…

• Patients with known active central nervous system (CNS) metastases.
• Subjects with other malignancy in five years before the first dose.
• Patients with tumor-related pain that cannot be controlled as determined.
• Patients with serious cardiovascular and cerebrovascular diseases.
• Uncontrollable third-space effusion, such as pleural effusion, pericardial effusion or peritoneal effusion.
• Patients with severe infections.
• History of immunodeficiency.
• History of autoimmune diseases.
• Active infection.
• Pregnant or nursing women.
• Known history of serious allergic reactions to the investigational product or its main ingredients.

Where it is running

• Shandong First Medical University Affiliated Cancer Hospital — Jinan, Shandong, China (enrolling)

Full record on ClinicalTrials.gov

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