Blood Flow-restricted Resistance Exercise to Promote Muscle Strength and Use in Adults With Incomplete Spinal Cord Injury

Completed

Conditions studied: Spinal Cord Injury Cervical

In brief

Recovery of arm and hand motor control is critical for independence and quality of life following incomplete spinal cord injury (iSCI). Blood flow-restricted resistance exercise (BFRE) has emerged as a potential treatment addressing this need, but treatment guidelines and research reporting effectiveness are sparse. The purpose of this work is to provide case reports of people with cervical iSCI who use BFRE supplemented by electrical stimulation (ES) to increase the strength and functional use of selected upper extremity muscles.

Key facts

Study ID

NCT06907381

Run by

Quality Living, Inc.

People needed

10

Starts

2025-04-01

Expected to finish

2026-06-24

Last updated by the study team

2026-06-25

Who can join

Age: 19 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Incomplete cervical spinal cord injury
• Resting blood pressure between 80/50 mmHg and 150/90 mmHg for at least three consecutive days
• Native speaker of English

You may not qualify if…

• Recent history of deep vein thrombosis or cardiovascular disease including uncontrolled hypertension or a blood-clotting disorder
• Routine experience of orthostatic hypotension as defined as a drop in systolic/diastolic blood pressure greater than 20/10 mmHg when engaging in physical activity
• Severe cognitive, communication, or behavioral disorder as determined by treatment team

Where it is running

• Quality Living, Inc. — Omaha, Nebraska, United States

Full record on ClinicalTrials.gov

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