RNA Assays for Endometriosis Detection and Diagnosis
Enrolling by invitation
Conditions studied: Endometriosis
In brief
Endometriosis is a common disease that affects up to 10% of women of reproductive age. Diagnosis, however, is typically delayed (up to 12 years) and is usually made after surgery. A key unmet need therefore is an accurate biomarker that can be used to detect the disease early. This study is a prospective trial to identify candidate mRNA-markers which can be used to aid in the diagnosis of this disease. It is a discovery/validation study that will identify and confirm a gene expression panel that is specific for endometriosis and provides a non-invasive tool for future use.
Key facts
- Study ID
- NCT06907303
- Run by
- Wren Laboratories LLC
- People needed
- 400
- Starts
- 2024-01-01
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2025-04-02
Who can join
Age: 20 and older, up to 35. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- For the endometriosis cohort
- a history of infertility more than 1 year
- age 20-35 years
- normal liver and kidney function, without gynaecological and other systemic disease
- Inclusion criteria for controls include normo-ovulatory history, aged between 20-35 years, who exhibit normal liver and kidney function, and do not have any systemic diseases including autoimmune disease.
You may not qualify if…
- For the endometriosis cohort
- polycystic ovary syndrome, hyperprolactinemia
- severe cardiovascular system, liver, kidney, and hematopoietic system disease
- autoimmune disease
- uterine fibroids, endometritis, non-vegetative ovarian cysts, ovarian malignancies, and internal genital tuberculosis
- Exclusion criteria for the controls includes gynaecological malignancies and genital tuberculosis.
Where it is running
- Wren Laboratories — Branford, Connecticut, United States
- University of Cape Town — Cape Town, South Africa
Full record on ClinicalTrials.gov
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