Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines

Recruiting now · Phase 3 · Has a placebo group

Conditions studied: Migraine

In brief

The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.

Key facts

Study ID

NCT06904287

Run by

Wake Forest University Health Sciences

People needed

100

Starts

2025-12-16

Expected to finish

2027-06-01

Last updated by the study team

2026-01-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years or older
• Able to provide informed consent
• English speaking
• Primary diagnosis of migraine. Patient with a previous diagnosis of migraine, who experience headaches with typical migraine features (e.g at least 2-3 of the following: recurrent, unilateral, pounding or throbbing in nature, associated with nausea), AND with a clinical exclusion of migraine mimics

You may not qualify if…

• Pregnancy defined as a positive urine HCG
• Allergy or sensitivity to study drug
• Stated history of renal insufficiency
• Documented history of myasthenia gravis
• Consumption of study drug within 48 hours prior to enrollment
• Previously enrolled in this trial during a different patient encounter

Where it is running

• Advocate Christ Medical Center Emergency Department — Oak Lawn, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.