The Effect of Propolis Administration on Cholesterol Level in Diabetic Type 2 Patients

Recruiting now · Phase 4 · Has a placebo group

Conditions studied: Diabetes Mellitus Type 2

In brief

The goal of this clinical trial is to learn if propolis administration works to change the level of Low Density Lipoprotein (LDL) and High Density Lipoprotein cholesterol (HDL) in diabetic type 2 patients. The main questions it aims to answer are: \- Is giving 1 drops/ 10kg/ times, twice daily for 8 weeks will change the level of LDL and HDL level in diabetic type 2 patients compared to placebo? Researchers will compare propolis to a placebo (a look-alike substance that contains no drug) to see if propolis works to change LDL and HDL cholesterol level. Participants will: * Take propolis or a placebo, 2 times daily with given dose (1 drops/10 kg/times) every day for 2 months * Visit the sub-district health centre once every 2 weeks for checkups * Get their blood checked before and after intervention

Key facts

Study ID

NCT06903546

Run by

Indonesia University

People needed

64

Starts

2025-03-18

Expected to finish

2025-07-31

Last updated by the study team

2025-04-03

Who can join

Age: 35 and older, up to 59. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Controlled Diabetes Mellitus type 2 with HbA1c <7.5%
• BMI 23-35 kg/m2
• On anti-cholesterol therapy

You may not qualify if…

• Using injection therapy (insulin or GLP-1 RA)
• History of bees product allergy
• Active smoker
• Consuming alcohol
• Altered liver (ALT>35 IU/L) and kidney (eGFR<90 mL/min) function
• Pregnant and breastfeeding women
• History of cardiovascular disease (heart attack, stroke)

Where it is running

• University of Indonesia Faculty of Biomedical Science — Jakarta, Indonesia (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.