Language Outcomes, Mechanisms, and Trajectories in Adults With and Without Developmental Language Disorder
Recruiting now
Conditions studied: Developmental Language Disorder
In brief
The investigators' overall objective is to characterize the long-term outcomes of Developmental Language Disorder (DLD) in adulthood and to identify specific cognitive mechanisms mediating these outcomes. To address their objectives, the investigators utilize a large, pre-existing dataset and participant pool from one of the most comprehensive examinations of DLD to date: the Iowa Longitudinal Study. The investigators will re-recruit subjects with DLD and with typical language from this historic cohort, who are now adults (30-35 years old). In Aim 1, the investigators will use measures from kindergarten through 10th grade and collect new outcome measures in adulthood to characterize the long-term outcomes of DLD. The investigators predict that adults with DLD will diverge from adults with TL in language skills that are more complex and higher-level language skills that are important for communication in the workplace. Further, the investigators predict a fanning effect: some children with DLD will "catch up" to their TL peers in adulthood, some will show evidence of a decline, and others will show stable trajectories. In Aim 2, the investigators measure real-time competition across written and spoken language using eye-tracking. According to speed of processing accounts adults with DLD may be slower than their TL peers to activate competitors and targets. According to working memory accounts adults with DLD will show sustained competitor activation. Further, the investigators predict that measures related to the dynamics of competition (speed of activation and timing of competitor suppression) will account for variation in language outcomes in adults.
Key facts
- Study ID
- NCT06898671
- Run by
- University of Iowa
- People needed
- 400
- Starts
- 2023-04-17
- Expected to finish
- 2027-07-01
- Last updated by the study team
- 2025-03-27
Who can join
Age: 30 and older, up to 35. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Adults with Developmental Language Disorder (DLD) and those with typical language (TL) between the ages of 28 and 40 years who participated in the Iowa Longitudinal Study(NIH-DC-19-90 \& P50 DC002746; IRB# 200106051, "Collaboration on Specific Language Impairment".)
- Aged 30-35
- Normal or corrected to normal vision
- Normal hearing
You may not qualify if…
- history of brain injury
- history of neural developmental disabilities
- not monolingual
Where it is running
- Wendell Johnson Speech and Hearing Center — Iowa City, Iowa, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.