Evaluation of Plasma Renin Concentrations in Cardiac Surgery
Running, not enrolling
Conditions studied: Cardiac Surgery With Cardiopulmonary Bypass
In brief
The purpose of this research is to learn more about how renin (a blood test) is affected by cardiopulmonary bypass, the heart-lung machine used during open heart surgery. Renin is a protein that may be elevated in response to low blood pressure or situations where organs do not receive sufficient oxygen. Renin may potentially be used as an indicator for specific treatments aimed to increase the blood pressure. This study will evaluate blood samples for renin concentration throughout the course of open heart surgery.
Key facts
- Study ID
- NCT06895213
- Run by
- Mayo Clinic
- People needed
- 100
- Starts
- 2025-04-14
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2026-08-10
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult persons 18 years of age or greater.
- Scheduled for an elective cardiac surgical procedure involving the use of cardiopulmonary bypass.
You may not qualify if…
- Surgery involving heart or lung transplantation or implant of a durable left ventricular assist device.
- Emergency cardiac surgery.
- Established diagnosis of any congenital heart disease.
- End-stage kidney disease receiving kidney replacement therapy before surgery.
Where it is running
- Mayo Clinic — Rochester, Minnesota, United States
Full record on ClinicalTrials.gov
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