Breastmilk in Response to a Bout of Exercise

Recruiting now

Conditions studied: Infant Development, Obesity, Childhood, Diabetes, Childhood-Onset

In brief

The purpose of this study is to unveil the mechanistic benefits of a bout of postpartum maternal exercise on infant health that are provided by breastmilk.

Key facts

Study ID

NCT06892483

Run by

Mayo Clinic

People needed

60

Starts

2025-04-21

Expected to finish

2028-09-25

Last updated by the study team

2026-06-24

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may not qualify if…

• Active coronary artery disease or heart failure.
• Participation in a structured exercise program ≥ 1 day/week in the "inactive" subcohort or < 3 days per week in the "active" subcohort.
• A known medical condition that in the judgment of the investigator might interfere with the completion of the protocol such as the following examples:
• Abnormal liver function test results (Transaminase >2 times the upper limit of normal
• Abnormal renal function test results (calculated GFR <60 mL/min/1.73m2);
• If on antihypertensive, thyroid, anti-depressant or lipid lowering medication, lack of stability on the medication for the past 2 months prior to enrollment in the study
• Uncontrolled thyroid disease (TSH undetectable or >10 mlU/L); testing required within three months prior to admission for subjects with a goiter, positive antibodies, or who are on thyroid hormone replacement, and within one year otherwise
• Abuse of alcohol or recreational drugs
• Active tobacco smoking within the past 3 months
• Infectious process not anticipated to resolve prior to study procedures (e.g. meningitis, pneumonia, osteomyelitis).
• Uncontrolled arterial hypertension (Resting diastolic blood pressure >90 mmHg and/or systolic blood pressure >160 mmHg) at the time of screening.
• A recent injury to body or limb, muscular disorder, use of any medication, any carcinogenic disease, or other significant medical disorder if that injury, medication or disease in the judgment of the investigator will affect the completion of the protocol
• Active pregnancy
• Restrictions on Use of Other Drugs or Treatments:
• Any other medication believed to be a contraindication to the subject's participation.

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.