Diffusion MRI for Quantitative Assessment of Myofascial Pain

Recruiting now

Conditions studied: Masticatory Myofascial Pain Syndrome

In brief

The purpose of this study is to assess the diagnostic accuracy of diffusion MRI for evaluation of the jaw muscles for patients with masticatory myofascial pain syndrome.

Key facts

Study ID

NCT06892041

Run by

Weill Medical College of Cornell University

People needed

90

Starts

2025-09-04

Expected to finish

2026-07-01

Last updated by the study team

2025-10-01

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Men and women 18-65 years of age
• Ability to give informed consent
• Symptoms meeting criteria for normal or latent/active temporomandibular myofascial pain

You may not qualify if…

• Contraindications to MRI scanning including severe obesity or difficulty in laying in a supine position, intracranial clips, metal implants, external metallic devices/objects/clips within 10mm of the head, suspected or confirmed metal in the eyes (history of welding or similar activity), claustrophobia, cardiac pacemaker or pacing wires
• Pregnancy or breast feeding
• Traumatic injury of masticatory muscles or temporomandibular joint within last 12 months
• Mandibular fracture within last 12 months
• Initiation of additional treatment of myofascial pain within the past 1 month
• Received masseter Botox within the last 4 months

Where it is running

• New York University — New York, New York, United States (enrolling)
• Weill Cornell Medicine — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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