Pharmacist-Led Treat-to-Target Urate Lowering Therapy in Patients With Gout

Starting soon · Not applicable

Conditions studied: Gout, Gouty Arthritis

In brief

This study will compare two different approaches to manage medications that lower uric acid levels. This study will be conducted at five VA medical centers across the United States and will take 4-5 years to complete. Individual participation will last up to two years.

Key facts

Study ID

NCT06887452

Run by

VA Office of Research and Development

People needed

310

Starts

2026-10-01

Expected to finish

2031-03-30

Last updated by the study team

2026-02-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• US Veterans over the age of 18 years with physician-diagnosed
• Documented hyperuricemia (SU >6.8 mg/dL)
• Satisfy ACR/EULAR gout classification criteria
• Report 1 or more flares in the prior 6 months
• Receipt of a new ULT prescription (allopurinol or febuxostat) initiated by a primary care provider or longer term ULT but otherwise satisfy the flare/SU criteria

You may not qualify if…

• Any patient intolerant or unable to take ULTs (allopurinol or febuxostat)
• Patients with a rheumatology encounter within the prior 3 months

Where it is running

• Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE — Omaha, Nebraska, United States
• VA Portland Health Care System, Portland, OR — Portland, Oregon, United States
• Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA — Philadelphia, Pennsylvania, United States
• VA Salt Lake City Health Care System, Salt Lake City, UT — Salt Lake City, Utah, United States
• VA Puget Sound Health Care System Seattle Division, Seattle, WA — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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