Multicentric Case Series of Uniportal Endoscopic Posterior Cervical Decompression for Cervical Spinal Stenosis

Recruiting now

Conditions studied: Spinal Stenosis Cervical

In brief

Cervical spinal stenosis is a condition that can cause pain, sensory disturbances, and motor deficits due to the compression of neural structures in the cervical spine. While conservative treatments such as physical therapy and pain management can help some patients, others with persistent neurological deficits may require surgical intervention. Traditional surgical approaches, including anterior decompression and posterior open surgery, have proven effective but carry risks such as vascular or nerve injuries and postoperative pain. This study evaluates a minimally invasive surgical approach called Posterior Uniportal Endoscopic Cervical Decompression as an alternative to traditional methods for patients with cervical spinal stenosis. The main objective is to assess changes in neurological deficits and disability related to cervical pain following this procedure. The study will also document hospitalization duration, surgical time, blood loss, and the incidence of postoperative complications. This multicenter, prospective case series will recruit 50 patients from three medical centers in Mexico. Participants must have symptomatic cervical spinal stenosis that persists despite at least three months of conservative treatment. Eligible patients will undergo Posterior Uniportal Endoscopic Cervical Decompression, a technique that allows precise nerve decompression through a small incision, minimizing damage to surrounding tissues. Standardized clinical assessment tools, including the modified Japanese Orthopaedic Association (mJOA) scale, Neck Disability Index (NDI), and Visual Analog Scale (VAS) for pain, will be used to evaluate outcomes at multiple time points over 12 months. By comparing patients' preoperative and postoperative evaluations, the study aims to determine whether Posterior Uniportal Endoscopic Cervical Decompression effectively improves neurological function and reduces disability while maintaining a favorable safety profile. Findings from this study could support the adoption of minimally invasive endoscopic techniques as a viable option for treating cervical spinal stenosis, potentially leading to faster recovery times and reduced surgical complications compared to traditional methods.

Key facts

Study ID: NCT06886802
Run by: TecSalud Investigación Clínica
People needed: 50
Starts: 2026-02-18
Expected to finish: 2027-02-01
Last updated by the study team: 2026-03-04

Who can join

Age: 18 and older, up to 74. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Provision of informed consent to participate in the study.
Patients with cervical canal stenosis grade I-III according to the Kang scale.
Radicular or myelopathic symptoms.
Having undergone complete conservative management, including physical therapy and analgesia, for at least 3 months.
Patients who have opted for posterior uniportal endoscopic cervical decompression for cervical canal stenosis.

You may not qualify if…

Inability to read or write.
Prior cervical surgeries at the levels to be treated.
Infectious symptoms or concomitant rheumatologic diseases.
Criteria of cervical vertebral instability.
Congenital spinal malformations.
Disc herniation at the same cervical level to be operated on.
Medullary hyperintensity on T2-weighted magnetic resonance imaging in the level(s) to be treated.

Where it is running

Hospital Zambrano Hellion, TecSalud — San Pedro Garza García, Nuevo León, Mexico (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.