PRP & PDO Threads in Treatment of Stress Incontinence

Recruiting now · Not applicable

Conditions studied: Stress Incontinence, Female

In brief

The study will include 10 women with pure or predominant SUI symptoms, with severe urodynamic stress incontinence on urodynamics defined as loss of urine with sudden increases in abdominal pressure: eg, coughing, sneezing, or laughing). This will be conducted at the Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University. The purpose of study is to evaluate the efficacy and safety of platelets rich plasma combined with PDO threads in the treatment of stress incontinence in Egyptian women.

Key facts

Study ID

NCT06885463

Run by

Al-Azhar University

People needed

10

Starts

2025-03-01

Expected to finish

2025-06-30

Last updated by the study team

2025-03-20

Who can join

Age: 20 and older, up to 45. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Nonpregnant Women with SUI
• Age between 20 to 45 years
• Patients had a history of failed conservative treatment
• Patients were on the waiting list for surgical treatment of SUI

You may not qualify if…

• Under anti-platelet agent treatment
• Under NSAIDs
• Platelet dysfunction syndrome
• Critical thrombocytopenia
• Hypofibrionogenaemia
• Sepsis
• Acute and chronic infections
• Chronic liver disease
• Anti-coagulation therapy
• History of malignancy
• Pregnancy
• history of active malignant pathology
• mental disorders making them unable to give consent
• genitourinary fistula
• pelvic organs prolapse stage >2 according to the Pelvic Organ Prolapse Quantification system, and detrusor overactivity on urodynamics.

Where it is running

• Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University. — Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.