Determination of the Frequency and Predictors of Difficult Intubation in Septoplasty Operations

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Conditions studied: Nasal Septum, Irregular, Nasal Septal Defect, Difficult Airway, Difficult Endotracheal Intubation, Predicted Difficult Airway

In brief

Deviated septum is among the most prevalent etiologies of nasal obstruction. Congenital or acquired deformities of the nasal septum have been demonstrated to result in partial obstruction of the airflow, thereby causing respiratory distress. Furthermore, studies have indicated a potential correlation between nasal congestion and Obstructive Sleep Apnoea Syndrome (OSAS). It is a well-documented phenomenon that patients suffering from nasal obstruction often exhibit an open mouth during sleep, a condition that has been shown to result in the narrowing of the pharyngeal lumen and the subsequent development of sleep-related breathing disorders, including snoring and sleep apnoea. Surgical intervention to correct a deviated nasal septum (commonly referred to as septoplasty) has been shown to reduce upper airway resistance by enhancing airflow, leading to a reduction in the severity of both snoring and OSAS. Numerous studies have demonstrated a robust correlation between a deviated nasal septum and asymmetric facial growth, including maxillary and mandibular abnormalities. While septoplasty is considered a minor surgical procedure with a low anaesthetic risk, concomitant obstructive sleep apnoea syndrome (OSAS) and facial asymmetry have been demonstrated to be associated with an increased risk of difficult intubation. Consequently, the development of preoperative assessment tests to predict difficult intubation is imperative for effective planning of the necessary preoperative preparation when such complications are anticipated. The present study therefore sought to evaluate the incidence of difficult airway in patients undergoing septoplasty. The secondary aim was to determine the predictive factors associated with difficult airway in patients undergoing septoplasty.

Key facts

Study ID

NCT06884592

Run by

Başakşehir Çam & Sakura City Hospital

People needed

300

Starts

2025-05-28

Expected to finish

2027-01-30

Last updated by the study team

2026-07-22

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Consenting patients,
• ASA-I-II
• Between the ages of 18 and 65,
• Difficult intubation and no history of facial trauma or congenital craniofacial deformity
• Patients with easy mask ventilation during the procedure
• Nasal obstruction due to deviated nasal septum,
• Patients who will receive general anaesthesia and undergo septoplasty surgery

You may not qualify if…

• Patients without consent
• Not in the appropriate age range,
• Patients who do not receive general anaesthesia and will not undergo septoplasty surgery,
• ASA-IV-V with ,
• Difficult intubation and a history of facial trauma or congenital craniofacial deformity
• Patients with easy mask ventilation during the procedure

Where it is running

• Başakşehir Çam and Sakura City Hospital — Başakşehir, Istanbul, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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