Reproducibility of Multiparametric Renal Magnetic Resonance Imaging on 1.5T MRI Scanners

Recruiting now · Not applicable

Conditions studied: Multiparametric MRI

In brief

This is an interventional, multicenter, prospective study involving healthy volunteers, to primarily assess the reproducibility of multiparametric renal MRI on 1.5T scanners. The study is also aimed at assessing possible differences in renal MRI reproducibility on 1.5T MRI scanners by sex and age, and assessing possible differences in renal MRI reproducibility across field strengths (1.5T vs 3T) in the subgroup of subjects enrolled in both RESPECT clinical study and in the current subproject.

Key facts

Study ID

NCT06884410

Run by

Mario Negri Institute for Pharmacological Research

People needed

48

Starts

2025-04-12

Expected to finish

2026-04-01

Last updated by the study team

2025-09-02

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Provision of written informed consent prior to any study specific procedures
• Male and female subjects aged [18-70] years
• Office SBP values < 140 mmHg and DBP values ≤ 90 mmHg, under no antihypertensive therapy
• Normal renal function defined as: estimated glomerular filtration rate [eGFR] ≥ 60mL/min/1.73m2 (using CKD-EPI Creatinine Equation)
• Negative result upon urine testing for haematuria or proteinuria.

You may not qualify if…

• Previous enrollment in the present substudy
• Contraindications to MRI including caustrophobia, pregnancy, cardiac pacemakers or other MRI-incompatible prostheses
• Ongoing therapy (e.g. for diabetes, dyslipidemia, or any acute disease)
• Past or current oncological pathology

Where it is running

• IRCCS Azienda Ospedaliero-Universitaria di Bologna — Bologna, BO, Italy (enrolling)
• Aarhus University Hospital — Aarhus, Denmark
• University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University — Mannheim, Germany
• Clínica Universidad de Navarra — Pamplona, Navarre, Spain

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.