JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

Recruiting now

Conditions studied: Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation, Patellofemoral Joint Dislocation, Patellofemoral Disorder

In brief

The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability. The main questions it aims to answer are: * What are the risk factors for recurrent patellar instability after MPFL reconstruction? * What functional outcomes do patients report after MPFL reconstruction? Participants undergoing MPFL reconstruction will answer survey questions about their knee and activity level 1 year and 2 years after surgery.

Key facts

Study ID

NCT06883396

Run by

Hospital for Special Surgery, New York

People needed

850

Starts

2023-01-01

Expected to finish

2027-12-01

Last updated by the study team

2026-02-13

Who can join

Age: 10 and older, up to 35. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 10-35 years old
• Recurrent patellar instability with at least one episode defined as either (1) a dislocated patella requiring reduction in the emergency department or (2) a convincing history for dislocation, associated with full giving way, and the following physical findings: (a) hemarthrosis or effusion, (b) tenderness along the medial retinaculum, and (c) apprehension when laterally directed force was applied to the patella or (3) MRI-documented dislocation with associated bone bruises

You may not qualify if…

• Previous ipsilateral knee surgery
• Obligatory/fixed/habitual patella dislocation or subluxation
• Unloadable inferior or lateral chondral damage on the patella that would require a tibial tubercle transfer for unloading purposes
• Pathologic tibiofemoral instability

Where it is running

• Scottish Rite for Children — Dallas, Texas, United States (enrolling)
• University of Florida — Gainesville, Florida, United States (enrolling)
• Midwest Orthopaedics at Rush — Chicago, Illinois, United States (enrolling)
• University of Iowa — Iowa City, Iowa, United States (enrolling)
• Massachusetts General Hospital — Boston, Massachusetts, United States (enrolling)
• Boston Children's Hospital — Boston, Massachusetts, United States (enrolling)
• Ohio State University Wexler Medical Center — Dublin, Ohio, United States (enrolling)
• Oregon Health & Science University — Portland, Oregon, United States (enrolling)
• Stanford University — Redwood City, California, United States (enrolling)
• NYU Langone Health — New York, New York, United States (enrolling)
• Hospital for Special Surgery — New York, New York, United States (enrolling)
• Duke Health — Wake Forest, North Carolina, United States (enrolling)
• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States (enrolling)
• Mayo Clinic — Rochester, Minnesota, United States
• Mount Sinai — New York, New York, United States
• Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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