The Management of Asymptomatic Carotid Stenosis

Recruiting now

Conditions studied: Carotid Artery Diseases, Carotid Stenosis

In brief

Carotid stenosis are asymptomatic if no hemispheric or retinal symptoms have appeared in the 6 months preceding the discovery of the stenosis. Asymptomatic carotid stenosis (ACS) accounts for about ¾ of all carotid lesions. The goal of treating carotid stenosis is to prevent a stroke. While carotid surgery is recommended in the elderly patients in cases of symptomatic carotid stenosis, that of ACS in patients over 75 years old, even when tight, remains subject to many controversies. Indeed, the debate, concerning the benefit to be expected from a surgical procedure or a possible angioplasty procedure, is not yet closed. The aim of our study, through a retrospective evaluation of the results of all consecutive carotid endarterectomy (CEA) and stenting in the participating center.

Key facts

Study ID

NCT06882954

Run by

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

People needed

500

Starts

2019-01-01

Expected to finish

2027-12-31

Last updated by the study team

2025-03-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Asymptomatic carotid stenosis
• Patient with degree of carotid stenosis greater than 80% measured by the maximum systolic velocity at the site of the stenosis which must have been greater than 250 cm/s
• Ultrasound characteristics of a possibly unstable plaque

You may not qualify if…

• Symptomatic carotid artery stenosis

Where it is running

• Fondazione Policlinico Universitario A. Gemelli IRCCS — Roma, RM, Italy (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.