Comparing Articular Noise and Its Perception Between Two Different Types of Total Knee Arthroplasty

Recruiting now · Not applicable

Conditions studied: Knee Osteoarthristis, Knee Replacement Arthroplasty, Knee Replacement, Total

In brief

Some patients complain of articular noise (such as clicking, snapping, cracking or popping) after a total knee replacement. Controversy remains about whether there is a correlation between articular noise and worse outcomes following a knee replacement. A study by Nam et al. on 1540 patients revealed an association between noise and residual symptoms 30 days after they received a total knee replacement. Conversely, a study by Kuriyama et al. on 60 patients revealed no correlation between noise and patient satisfaction after 1 year of receiving a total knee replacement. The incidence of noise following a knee replacement has rarely been studied as a primary outcome. Like pain, it could be considered an important patient-reported outcome to assess patient satisfaction. The study aims to compare the prevalence of patient-perceived noise of an ultra-congruent total knee prosthesis (Score 2, Amplitude) versus a posterior-stabilized total knee prosthesis (Anatomic, Amplitude).

Key facts

Study ID

NCT06880497

Run by

Elsan

People needed

170

Starts

2025-12-24

Expected to finish

2028-12-01

Last updated by the study team

2026-03-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients receiving a primary TKA
• Signed informed consent
• Patients affiliated to a social security scheme
• Patients willing and able to comply with study protocol requirements based on the investigator's judgment.

You may not qualify if…

• History of knee surgery on the concerned/studied knee (except arthroscopic surgery)
• Patients presenting coronal deformities > 20°, varus laxity > 10° and/or valgus laxity > 15°
• Patients receiving revision TKA
• Pregnancy or breast-feeding
• Patients with protected status under articles L1121-6, LL121-8 and L1122-2 of the French Public Health Code
• Unable to comply with study procedures, based on the investigator's judgment.

Where it is running

• St Marguerite clinic — Auxerre, France (enrolling)

Full record on ClinicalTrials.gov

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