The Impact of Endoscopic Endonasal Skull Base Surgery on Olfaction

Recruiting now

Conditions studied: Meningioma, Pituitary Disease, Pituitary Adenoma, Craniopharyngioma, Endoscopic Pituitary Surgery, Olfactory Dysfunction

In brief

In this study, the research team will investigate the incidence and etiology of olfactory dysfunction following endoscopic endonasal skull base surgery, by combining clinical assessments with histomolecular analysis.

Key facts

Study ID

NCT06874426

Run by

Universitaire Ziekenhuizen KU Leuven

People needed

154

Starts

2025-03-18

Expected to finish

2029-09-01

Last updated by the study team

2025-04-23

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients scheduled for endoscopic endonasal skull base surgery

You may not qualify if…

• Pre-existing anosmia
• Patients has a history of previous endoscopic endonasal skull base surgery

Where it is running

• KU Leuven — Leuven, Vlaams-Brabant, Belgium (enrolling)
• Max Planck Research Unit for Neurogenetics — Frankfurt am Main, Hesse, Germany
• Leiden University Medical Center — Leiden, South Holland, Netherlands

Full record on ClinicalTrials.gov

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