Practical Geriatric Assessment (PGA) Implementation Strategies and Correlative Evaluations (PACE-70)
Recruiting now
Conditions studied: Geriatric Assessment, Advanced Cancer, Toxicity
In brief
The use of a geriatric assessment to inform oncologic care for older persons with cancer is an evidence-based practice that improves patient-clinician communication, reduces treatment-related toxicity, and is recommended by national guidelines. However, the implementation of a geriatric assessment can be time-consuming and burdensome, leading to suboptimal use in clinical practice. Developed and endorsed by the American Society for Clinical Oncology (ASCO), the Practical Geriatric Assessment (PGA) is designed to improve clinical usability and adoption, but its implementation in real-world settings has not been evaluated. The PACE-70 study aims to evaluate PGA implementation and resultant chemotherapy dose modification among older adults with advanced cancer treated in a community setting. An exploratory aim will evaluate how the PGA, body composition (via abdominal computed tomography scan) and step count monitoring (via FitBit) correlate with chemotherapy toxicity and other clinical outcomes.
Key facts
- Study ID
- NCT06870617
- Run by
- Abramson Cancer Center at Penn Medicine
- People needed
- 150
- Starts
- 2025-07-01
- Expected to finish
- 2026-10-01
- Last updated by the study team
- 2026-08-06
Who can join
Age: 70 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Penn Medicine Princeton Medical Center — Princeton, New Jersey, United States (enrolling)
- Pennsylvania Hospital — Philadelphia, Pennsylvania, United States (enrolling)
- Lancaster General Hospital — Lancaster, Pennsylvania, United States
Full record on ClinicalTrials.gov
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