Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Surgical Repair of Digital Nerve Injuries

Recruiting now · Not applicable

Conditions studied: Digital Nerve Injury, Nerve Injury, Nerve Reconstruction, Nerve Trauma, Digital Nerve Lesion

In brief

The goal of this clinical study is to evaluate if a period of electrical stimulation delivered during the surgical repair procedure can speed up nerve healing.

Key facts

Study ID

NCT06867185

Run by

Checkpoint Surgical Inc.

People needed

60

Starts

2025-04-24

Expected to finish

2027-03-01

Last updated by the study team

2026-01-09

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-80 years
• Candidate for surgical intervention under general anesthesia.
• Require primary nerve injury repair in at least 1 digital nerve.
• Following resection, have a resulting nerve gap of ≤ 10mm.
• Able to complete tension-free end-to-end direct repair, or repair with a conduit, autograft, or allograft with a length ≤15mm
• Signed and dated informed consent form.

You may not qualify if…

• Severe comorbid conditions, such as arrhythmia or congestive heart failure, preventing surgery under general anesthesia.
• Nerve repair occurring >1 month post-injury.
• Incomplete nerve transection.
• Injury requiring replantation of target digit
• Injury distal to the distal interphalangeal joint.
• Injury proximal to branching into the proper or common digital nerves.
• Injuries to both digital arteries of an affected digit.
• History of neuropathy, diabetic neuropathy, or any other known neuropathy
• History of chronic ischemic condition of the upper extremity
• Cognitive impairment preventing the ability to provide consent, follow post-operative instructions, or complete clinical assessments.

Where it is running

• Indiana Hand to Shoulder Center — Indianapolis, Indiana, United States (enrolling)
• University of Missouri Department of Orthopaedic Surgery — Columbia, Missouri, United States (enrolling)
• Washington University in St Louis, Department of Orthopedic Surgery — St Louis, Missouri, United States (enrolling)
• The Ohio State Univeristy - Department of Plastic and Reconstructive Surgery — Columbus, Ohio, United States (enrolling)
• Harborview Medical Center - University of Washington — Seattle, Washington, United States (enrolling)

Full record on ClinicalTrials.gov

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