Evaluating Dyspnea in Autoimmune Myasthenia Gravis "Why am I Short of Breath?"

Recruiting now

Conditions studied: Myasthenia Gravis, Dyspnea

In brief

Individuals with MG (IwMG) experience shortness of breath that may be activity-related, occur at rest and even happen during sleep. Dyspnea is a complex, multidimensional and multifactorial symptom involving sensory perception, cognition and emotion. Identifying the cause(s) of dyspnea in MG may assist in finding therapeutic strategies, reducing discomfort, improving QoL and potentially limiting respiratory deterioration and incidence of MG crisis.

Key facts

Study ID

NCT06866652

Run by

Institut de Myologie, France

People needed

50

Starts

2026-04-08

Expected to finish

2028-06-01

Last updated by the study team

2026-05-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18
• Confirmed diagnosis of autoimmune MG
• Shortness of breath in daily life: score 1 or 2 on the respiration item on the MG- activities of daily living score
• Signed consent form
• Affiliated to or beneficiary of a social security scheme

You may not qualify if…

• Known Pregnancy
• Known respiratory disorder (other than MG)
• Recent (within past 4 weeks) respiratory infection
• Current MG crisis or exacerbation (necessitating increase in MG medication \&/or hospital admission)
• No dyspnea - score 0 or 3 on the respiration item on the MG- activities of daily living score
• Severe cognitive impairment/guardianship

Where it is running

• Institute of Myology — Paris, France (enrolling)

Full record on ClinicalTrials.gov

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