Well-being in IBS: Strengths and Happiness (WISH) 2.0
Recruiting now · Not applicable
Conditions studied: Irritable Bowel Syndrome
In brief
The purpose of this study is to examine the feasibility, acceptability, preliminary effects, and candidate gut-brain mechanisms of an optimized positive psychology (PP) intervention for patients with irritable bowel syndrome (IBS), entitled "WISH," compared to an educational control intervention.
Key facts
- Study ID
- NCT06866106
- Run by
- Massachusetts General Hospital
- People needed
- 50
- Starts
- 2025-10-30
- Expected to finish
- 2028-08-01
- Last updated by the study team
- 2026-06-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- IBS Diagnosis: Adult patients with an IBS diagnosis meeting standardized Rome IV diagnostic criteria.
- Language and communication: English fluency and access to a phone.
You may not qualify if…
- Presence of inflammatory bowel disease or other structural/biochemical primary gastrointestinal illness that better explains IBS-like symptoms: As reported by the patient, their physician, and/or documented in the medical record.
- Severe psychiatric illness: Current manic episode, psychosis, or active substance use disorder diagnosed via the Mini International Neuropsychiatric Interview (MINI) or Diagnostic Interview for Anxiety, Mood, and OCD and Related Neuropsychiatric Disorders (DIAMOND).
- Cognitive impairment: Assessed using a six-item cognitive screen developed for research.
- Presence of atrial fibrillation or a cardiac pacemaker, or daily use of beta blocking medication: As reported by the patient and/or documented in the medical record.
- Plans to start or participate in another new behavioral health intervention or psychotherapy during the study period.
Where it is running
- Massachusetts General Hospital — Boston, Massachusetts, United States (enrolling)
Full record on ClinicalTrials.gov
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