A Study to Investigate Tonlamarsen for the Treatment of Adults With Uncontrolled Hypertension (KARDINAL)
Completed · Phase 2 · Has a placebo group
Conditions studied: Hypertension
In brief
The purpose of this study is to evaluate the blood pressure (BP)-lowering efficacy of tonlamarsen in adult participants who, despite taking 2 or more antihypertensive medications, have not achieved their target blood pressure (BP).
Key facts
- Study ID
- NCT06864104
- Run by
- Kardigan, Inc.
- People needed
- 206
- Starts
- 2025-04-10
- Expected to finish
- 2026-03-17
- Last updated by the study team
- 2026-03-31
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Pinnacle Research Group — Anniston, Alabama, United States
- Achieve Clinical Research, LLC — Birmingham, Alabama, United States
- Elite Clinical Studies — Phoenix, Arizona, United States
- Del Sol Research Management, LLC — Tucson, Arizona, United States
- Cardiology and Medicine Clinic — Little Rock, Arkansas, United States
- North Coast Cardiology — Encinitas, California, United States
- Orange County Research Center — Lake Forest, California, United States
- Clinical Trials Research — Lincoln, California, United States
- American Institute of Research — Los Angeles, California, United States
- Homestead Associates in Research, Inc. — Homestead, Florida, United States
- Jacksonville Center for Clinical Research — Jacksonville, Florida, United States
- Suncoast Clinical Research, Inc. — New Port Richey, Florida, United States
- Progressive Medical Research — Port Orange, Florida, United States
- Agile Clinical Research Trials, LLC — Atlanta, Georgia, United States
- Velocity Clinical Reseach — Savannah, Georgia, United States
- Eagle Clinical Research — Chicago, Illinois, United States
- Clinical Investigation Specialists, Inc. — Gurnee, Illinois, United States
- Koch Family Medicine Clinical Research — Morton, Illinois, United States
- Tandem Clinical Research GI, LLC — Marrero, Louisiana, United States
- IMA Clinical Research — Monroe, Louisiana, United States
- DelRicht Clinical Research - New Orleans — New Orleans, Louisiana, United States
- ActivMed Practices & Research, LLC — Methuen, Massachusetts, United States
- Oakland Medical Research Center — Troy, Michigan, United States
- Olive Branch Family Medical Center — Olive Branch, Mississippi, United States
- Richmond University Medical Center — Staten Island, New York, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.