In Vivo Dosimetry for Brachytherapy Study
Recruiting now
Conditions studied: Prostate Cancer, Gynaecological Cancer
In brief
The main study aim is the investigate the clinical use of in vivo dosimeters (small measurement devices) for brachytherapy (internal radiotherapy).
Key facts
- Study ID
- NCT06863090
- Run by
- East and North Hertfordshire NHS Trust
- People needed
- 20
- Starts
- 2025-03-03
- Expected to finish
- 2026-03-01
- Last updated by the study team
- 2025-03-11
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged 18 years and above
- Patients receiving HDR brachytherapy using iridium-192 (192Ir) radioactive source either as a monotherapy or in combination with external beam radiotherapy for:
- histologically/radiologically proven primary or locally recurrent prostate cancer
- locally advanced gynaecological malignancy in the primary and recurrent setting
- primary cervix carcinoma (squamous, adenocarcinoma, adenosquamous) FIGO IB2-IVA
- primary vulval FIGO I-IVA
- primary vaginal FIGO I-IVA
- primary endometrial cancer FIGO Stage I-IVA (not suitable for surgery)
- endometrial cancer receiving adjuvant vaginal vault brachytherapy
- recurrent cervix, vulval, vaginal or endometrial cancer suitable for brachytherapy as discussed in a regional gynae-oncology multidisciplinary meeting.
- World Health Organisation (WHO) or Eastern Cooperative Oncology Group (ECOG) performance status 0-2
You may not qualify if…
- Previous brachytherapy exposure to the treatment site
- Patients unable to give informed consent
- Patients unable to have a regional or general anaesthetic
- Patients with the following medical conditions: coagulopathies, history of another primary malignancy, known allergy or sensitivity to study materials; previous or current fistulae
- Not able to understand the implications of participating in the study in English
- Patients with recent (within the last 6 months) or currently participating in interventional research
Where it is running
- Mount Vernon Cancer Centre — Northwood, Middlesex, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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