Effect of Point-of-care Analysis of Ultrasensitive Troponin I on Length of Hospital Stay in Patients With Cardiac Chest Pain (POC Troponina)

Recruiting now · Not applicable

Conditions studied: Acute Coronary Syndromes (ACS), Troponin I, Point-of-Care Testing

In brief

This clinical study aims to compare two different methods for measuring high-sensitivity troponin I, a key biomarker used to diagnose heart attacks. The primary research question is: Does the use of the Atellica VTLi kit from Siemens for high-sensitivity troponin I (hs-cTnI) testing at the point of care (POC) significantly reduce the average time from admission to hospital discharge compared to the conventional laboratory methodology using the Alinity i kit from ABBOTT? Participant will: * Patients aged ≥ 18 years. * Patients arriving in the emergency room with symptoms suggestive of ACS, with onset of pain between 3 and 12 hours after arrival, in whom serial troponin dosing is planned for investigation. * Signature of the Informed Consent Form (ICF). Researchers will analyze whether the point-of-care testing method helps speed up the hospital discharge process compared to the standard laboratory approach. They will also compare the accuracy of the test results, the time taken for clinical decisions, and the overall cost-effectiveness of the two methods.

Key facts

Study ID: NCT06861582
Run by: University of Sao Paulo
People needed: 200
Starts: 2025-03-10
Expected to finish: 2026-03-01
Last updated by the study team: 2025-04-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Patients aged ≥ 18 years.
Patients arriving in the emergency room with symptoms suggestive of ACS, with onset of pain between 3 and 12 hours after arrival, in whom serial troponin dosing is planned for investigation.
Signature of the Informed Consent Form (ICF).

You may not qualify if…

Patients presenting with ACS with ST-segment elevation on the 12-lead ECG on arrival at hospital.
Patients with conditions that interfere with the interpretation of troponin dosage (chronic renal failure, cancer, chronic lung diseases).
Pregnant or breastfeeding patients.
Patients already included in other clinical research protocols.

Where it is running

Instituto do Coração HCFMUSP — São Paulo, Brazil (enrolling)

Full record on ClinicalTrials.gov

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