Effect of Patient Preference for Intraoperative Opioid Use on Early Postoperative Quality of Recovery

Completed · Not applicable

Conditions studied: Opioid Analgesia, Quality of Recovery (QoR-15), Outcome Assessment, Opioid Free Anesthesia

In brief

Substituting the administration of opioids with a combination of alternative analgesics, known as opioid-free anesthesia (OFA), is gaining in popularity today and is typically administered as part of a larger multimodal strategy. However, OFA adoption is not as common today as one could expect from the potential benefits of limiting opioid use and patient involvement in the decision may impact its adoption. Relevant shared decision-making process with patients concerning the use or limited use of opioids could improve patient autonomy and empowerment. There have been no studies that have evaluated patient preference regarding opioid use and its potential impact on the quality of recovery. The aim of this study is to compare the effect of patient preference on intraoperative opioid use on early postoperative quality of recovery following moderate risk laparoscopic/robotic abdominal surgery.

Key facts

Study ID

NCT06855641

Run by

University of California, Los Angeles

People needed

240

Starts

2025-03-24

Expected to finish

2025-06-18

Last updated by the study team

2025-06-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age >18 years.
• Undergoing elective intermediate risk surgery under general anesthesia (robotic or laparoscopic assisted urological, gynecological or abdominal surgery).
• American Society Anesthesiologists physical status classification system grades of I-IV.
• English speaking.
• Informed consent signed.

You may not qualify if…

• Diagnosis of chronic pain
• Preoperative prescribed opioids
• Pregnancy or lactation.
• History of mental disorders.
• Contraindications to study drug (lidocaine, magnesium, dexmedetomidine, ketamine)
• Patient is participating in another interventional trial
• Patient is under judicial protection or is an adult under guardianship.

Where it is running

• Ronald Reagan UCLA Medical Center — Los Angeles, California, United States
• UCLA Ronald Reagan medical center — Los Angeles, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.