Oral Ketorolac for IUD Pain Reduction

Enrolling by invitation · Phase 2 · Has a placebo group

Conditions studied: IUD Insertion Pain

In brief

To determine if oral ketorolac given at different timepoints prior to intrauterine device (IUD) insertion influences pain experienced during this procedure.

Key facts

Study ID

NCT06853327

Run by

University of North Carolina, Chapel Hill

People needed

108

Starts

2025-05-23

Expected to finish

2026-06-30

Last updated by the study team

2025-05-30

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• 18 years or older
• Able to consent
• Desires IUD insertion

You may not qualify if…

• IUD placement under sedation or oral anxiolytic
• IUD replacement (removal with insertion)
• Daily narcotic or NSAID use
• Contraindications to IUD placement
• Current: pregnancy, genital/pelvic infection
• Lifetime history: uterine anomaly, pelvic inflammatory disease, allergy to levonorgestrel or copper
• Contraindications to ketorolac
• Current: weight under 50 kilograms
• Lifetime history: allergy to NSAIDs, liver disease, renal disease, peptic ulcer disease, cerebrovascular bleeding, gastrointestinal bleeding

Where it is running

• University of North Carolina - Hillsborough Campus — Hillsborough, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.