Efficacy of Selective Laser Trabeculoplasty Targeting Nasal Versus Inferior 180-degree
Completed · Not applicable
Conditions studied: Open Angle Glaucoma
In brief
The purpose of this study to optimize Selective Laser Trabeculoplasty (SLT) application when used in the management of open angle glaucoma (OAG)
Key facts
- Study ID
- NCT06851546
- Run by
- Mayo Clinic
- People needed
- 13
- Starts
- 2025-01-06
- Expected to finish
- 2025-11-10
- Last updated by the study team
- 2026-01-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18 years and older
- Ability to comprehend the study procedures and agreement to proceed with primary SLT treatment
- Diagnosis of primary or secondary open angle glaucoma or glaucoma suspects with ocular hypertension
- Bilateral disease
- Pre-SLT IOP >21 mmHg measured at least twice during patient's lifetime with or without medication
- Open angles with moderate to intense trabecular pigmentation
- Mild to moderate visual field defects (24-2 standard mean deviations better than the Swedish interactive thresholding algorithm standard of 12 dB)
- No adequate IOP control (low treatment compliance, substantial adverse effects with eyedrops, and at least 2 IOP measurements higher than the individualized target IOP)
You may not qualify if…
- Unwilling or unable to give consent
- Unable to attend scheduled post-operative visits
- Previous history of either laser treatment or intraocular surgery, except for non-complicated cataract surgery (performed >6 months before SLT)
- History of ocular trauma
- Narrow angles
- Retinal detachment
- Active iris neovascularization or active proliferative retinopathy
- Active uveitis
- Monocular patients
- Current use of steroids (ocular, periocular, or systemic)
Where it is running
- Mayo Clinic in Rochester — Rochester, Minnesota, United States
- Eye Care Centre, Victoria General Hospital — Halifax, Nova Scotia, Canada
Full record on ClinicalTrials.gov
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