Comparing Thoracolumbar Interfascial and Quadro Iliac Plane Blocks on Postoperative Opioid Use Following Lumbar Microsurgery
Recruiting now · Not applicable
Conditions studied: Lumbar Microdiscectomy, Nerve Block
In brief
Lumbar microdiscectomy is a commonly used surgical procedure for treating herniated discs. Effective postoperative analgesia is crucial for early mobilization and functional recovery. Uncontrolled postoperative pain can delay recovery, increase the risk of opioid dependence, and lead to respiratory complications. Although opioid analgesics effectively reduce pain, they can cause side effects such as nausea, vomiting, respiratory depression, and dependency. Therefore, non-opioid analgesic methods are preferred for patient safety and comfort. Recently, regional anesthesia techniques such as the Thoracolumbar Interfascial Plane (TLIP) block and the Quadro Iliac Plane Block have been introduced for postoperative pain management in lumbar surgeries. However, there are not enough studies comparing the superiority of these two methods. Study Objective: The primary aim of this study is to evaluate the effects of ultrasound-guided TLIP and Quadro Iliac Plane Blocks on postoperative opioid consumption after lumbar microsurgery. The secondary aim is to compare opioid-related side effects (such as nausea, vomiting, respiratory depression, etc.) and postoperative NRS pain scores between the groups.
Key facts
- Study ID
- NCT06851533
- Run by
- Medipol University
- People needed
- 90
- Starts
- 2025-03-10
- Expected to finish
- 2026-12-10
- Last updated by the study team
- 2026-07-27
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged 18 to 80 years
- American Society of Anesthesiologists (ASA) physical status I to III
- scheduled for lumbar microdiscectomy surgery
You may not qualify if…
- Known allergy to local anesthetics
- Any other significant drug allergies related to the study interventions
- Pregnancy
- Pre-existing psychiatric or neurological disorders
- Inability to provide informed consent
Where it is running
- Medipol University — Istanbul, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
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