Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer
Recruiting now · Phase 2
Conditions studied: Locally Advanced Pancreatic Adenocarcinoma
In brief
The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer.
Key facts
- Study ID
- NCT06850623
- Run by
- EXACT Therapeutics AS
- People needed
- 25
- Starts
- 2025-06-19
- Expected to finish
- 2027-07-15
- Last updated by the study team
- 2026-04-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Not deemed suitable for primary curative surgery and have radiographic and pathological disease consistent with inoperable LAPC or borderline resectable pancreatic cancer.
- Suitable to receive treatment with mFOLFIRINOX according to the Investigator's assessment.
You may not qualify if…
- Any prior anti-cancer treatment for pancreatic cancer (e.g. chemotherapy, surgery, radiation). Palliative bypass procedure and bile duct stenting are allowed.
Where it is running
- HonorHealth Research Institute — Scottsdale, Arizona, United States (enrolling)
- Stanford Cancer Center Palo Alto — Stanford, California, United States (enrolling)
- Beth Israel Deaconess Medical Center - Division of Hematology/Oncology — Boston, Massachusetts, United States (enrolling)
- Henry Ford Centre — Detroit, Michigan, United States (enrolling)
- Sidney Kimmel Cancer Center, Thomas Jefferson University Hospital — Philadelphia, Pennsylvania, United States (enrolling)
- Allegheny General Hospital — Pittsburgh, Pennsylvania, United States (enrolling)
- Brown University Cancer Institute — Providence, Rhode Island, United States (enrolling)
- CAMBRIDGE CANCER TRIALS CENTRE-Addenbrooke's Hospital — Cambridge, Cambridge, United Kingdom (enrolling)
- Gary Weston Centre- Imperial College Healthcare- Du Cane Road — Hammersmith, London, United Kingdom (enrolling)
- The Royal Marsden- Downs Road — Sutton, Surrey, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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