Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios
Recruiting now · Not applicable
Conditions studied: Gastric Lesion, Gastritis, Upper Gastrointestinal Bleeding (UGIB), Gastric Dysplasia, Gastric Ulcer, Gastric Neoplasms
In brief
The goal of this clinical trial is to evaluate the diagnostic accuracy of the AI-integrated Capsule Gastroscopy (ACG) system in simulated home-use conditions for detecting upper gastrointestinal (UGI) abnormalities. It will also compare the diagnostic accuracy and time efficiency of AI-assisted interpretation versus manual reading of ACG data. The main questions it aims to answer are: What is the diagnostic accuracy of the ACG system, using conventional esophagogastroduodenoscopy (EGD) as a standard of reference? Does AI-assisted ACG reading improve diagnostic accuracy or reduce reading time compared to manual ACG video reading? Researchers will compare ACG results to conventional EGD findings (standard of reference) to determine if ACG can serve as a reliable method for UGI disease detection in home scenarios. Participants will: Undergo an ACG examination in a simulated home environment. Complete an EGD procedure within 24 hours post-ACG ingestion.
Key facts
- Study ID
- NCT06848400
- Run by
- Nanfang Hospital, Southern Medical University
- People needed
- 482
- Starts
- 2025-03-03
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2025-07-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Aged 18 years or older.
- Individuals meeting the following criteria:
- i. Healthy volunteers; ii. Suspected presence of gastrointestinal diseases, with one or more of the following clinical symptoms: abdominal pain, nausea, vomiting, hematemesis, black or bloody stools, loss of appetite, bloating, or indigestion; iii. Follow-up of gastric lesions post-endoscopic resection.
- Willing to participate voluntarily in the clinical trial and provide written informed consent.
- Capable of communicating with researchers and complying with trial requirements.
You may not qualify if…
- Pregnant individuals.
- Individuals at high risk of gastrointestinal obstruction, including those identified as being at risk of gastrointestinal stenosis based on the Gastrointestinal Stenosis Assessment Form, those in whom gastrointestinal obstruction cannot be clinically excluded, or individuals with a history of gastrointestinal surgery, severe motor dysfunction, or pseudobulbar palsy.
- Individuals with swallowing dysfunction.
- Individuals deemed unfit for surgery or unwilling to undergo any surgical procedures.
- Participants who are unable to comprehend and/or comply with physician instructions during the examination.
- Individuals with other medical risks that contraindicate the use of a capsule gastric endoscopy system, or those deemed unsuitable for participation in this study at the discretion of the investigator.
Where it is running
- Guangdong Provincial Hospital of Traditional Chinese Medicine — Guangzhou, Guangdong, China (enrolling)
- Second Affiliated Hospital of Guangzhou Medical University — Guangzhou, Guangdong, China (enrolling)
- Nanfang Hospital, Southern Medical University — Guangzhou, Guangdong, China (enrolling)
- Renhua People's Hospital — Shaoguan, Guangdong, China (enrolling)
- Longgang District People's Hospital of Shenzhen — Shenzhen, Guangdong, China (enrolling)
- Pingshan People's Hospital — Shenzhen, Guangdong, China (enrolling)
- Zhuhai People's Hospital — Zhuhai, Guangdong, China (enrolling)
- Wuxi People's Hospital. — Wuxi, Jiangsu, China (enrolling)
- Ganzhou People's Hospital — Ganzhou, Jiangxi, China (enrolling)
- Mianyang Central Hospital — Mianyang, Sichuan, China (enrolling)
- Prince of Wales Hospital of Hong Kong — Hong Kong, Hong Kong (enrolling)
- Fondazione Poliambulanza Istituto Ospedaliero — Brescia, Italy
Full record on ClinicalTrials.gov
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