The Clinical Utility of DNA Methylation Testing in Patient-collected Urine and Vaginal Samples to Detect Endometrial Cancer: a Case-control Study
Recruiting now
Conditions studied: Endometrial Cancer
In brief
The goal of this observational case-control study is to investigate the use of DNA-methylation testing in patient-collected urine and vaginal samples to detect endometrial cancer. The study aims to answer the following questions: * Can DNA methylation testing in vaginal and full-void urine samples distinguish endometrial cancer cases from healthy controls? Researchers will compare patient-collected urine and vaginal samples from patients with diagnosed endometrial cancer (cases) to gynaecologically and oncologically healthy controls (controls). Participants will * take a urine and vaginal sample at the hospital. * answer a questionnaire regarding acceptability and preferences of self-sampling methods. * answer a lifestyle questionnaire.
Key facts
- Study ID
- NCT06846775
- Run by
- University of Aarhus
- People needed
- 120
- Starts
- 2025-04-15
- Expected to finish
- 2028-01-30
- Last updated by the study team
- 2026-01-26
Who can join
Age: 60 and older. Sex: female. Healthy volunteers: accepted.
Where it is running
- Department of Obstetrics and Gynaecology, Aarhus University Hospital — Aarhus N, Denmark (enrolling)
- Department of Obstetrics and Gynaecology, Odense University Hospital — Odense, Denmark (enrolling)
- Department of Orthopaedics, Randers Regional Hospital — Randers, Denmark (enrolling)
Full record on ClinicalTrials.gov
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