Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease
Recruiting now · Not applicable
Conditions studied: Major Adverse Cardiovascular Events (MACE), Prevention, Coronary Artery Disease(CAD), CT Angiography
In brief
The primary objective of this study is to evaluate whether a management strategy based on coronary computed tomography angiography (CCTA) for patients with non-obstructive coronary artery disease can improve the LDL-C target achievement rate compared to a traditional management strategy without follow-up CCTA, thereby reducing the incidence of major adverse cardiovascular and cerebrovascular events over a 3 years period, including all-cause mortality, myocardial infarction, ischemia driven revascularation and stroke.
Key facts
- Study ID
- NCT06843005
- Run by
- Zhang longjiang,MD
- People needed
- 3100
- Starts
- 2025-02-28
- Expected to finish
- 2028-12-30
- Last updated by the study team
- 2026-03-24
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age between 18 and 80 years old;
- Known patients with non-obstructive coronary artery disease (disease duration ≥2 years);
- Patients who agree to undergo follow-up CCTA examinations and cooperate in completing follow-up observations.
You may not qualify if…
- Patients who have experienced ACS or PCI/CABG;
- Patients who have experienced adverse cardiovascular and cerebrovascular events;
- Patients who have undergone follow-up CCTA or DSA examinations before enrollment;
- Patients with severe hepatic and renal dysfunction;
- Patients with contraindications to CCTA examinations;
- Patients with poor initial CCTA image quality or data loss.
Where it is running
- Research Institute Of Medical Imaging Jinling Hospital — Nanjing, Jiangsu, China (enrolling)
Full record on ClinicalTrials.gov
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