Role of Corneal Nerves in Dry Eye Disease
Recruiting now
Conditions studied: Dry Eye Disease (DED), Dry Eye, Dry Eye Sensation, Corneal Nerve
In brief
This study aims to determine whether corneal nerve function and morphology are affected by tear film instability and ocular surface homeostasis loss. Additionally, it seeks to investigate whether these factors vary based on the severity of dry eye symptoms.
Key facts
- Study ID
- NCT06841471
- Run by
- Daniela Nosch
- People needed
- 140
- Starts
- 2025-02-20
- Expected to finish
- 2025-12-01
- Last updated by the study team
- 2025-03-11
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Group with DED: Diagnosis of DED based on the TFOS DEWS II report
- Group without DED: No diagnosis of DED
You may not qualify if…
- Exclusion criteria:
- Systemic disease that may affect ocular health and innervation
- injury or history of operations on the anterior or posterior segment of the eye, which can affect the corneal structure and physiology
- regular application of systemic or ocular medication known to affect the tear film except from DED medications
- eye drops or makeup on the day of measurement.
- Remarks:
- Contact lens wearers are asked not to wear contact lenses for 1 week before the first appointment.
- Participant with DED medications will be asked to use only conservative-free eye drops on the days of examination
Where it is running
- Institute of Optometrym FHNW — Olten, Switzerland (enrolling)
Full record on ClinicalTrials.gov
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