Treating Word Finding Difficulties in Traumatic Brain Injury With HD-tDCS

Completed · Not applicable · Has a placebo group

Conditions studied: Traumatic Brain Injury, Cognitive Change, Word Finding Difficulty, Acquired Brain Injury

In brief

The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., pre-supplementary motor area) thought to aid in memory will improve verbal retrieval in civilian (non-military, non-veteran) participants with histories of traumatic brain injuries. The primary outcome measures are neuropsychological assessments of verbal retrieval, and the secondary measures are neuropsychological assessments of other cognitive abilities and electroencephalography (EEG) measures. Additionally, the study will examine the degree to which baseline assessments of cognition, concussion history, structural brain imaging, and EEG predict responses to treatment over time, both on assessments administered within the intervention period and at follow-up.

Key facts

Study ID

NCT06840808

Run by

The University of Texas at Dallas

People needed

14

Starts

2024-12-01

Expected to finish

2025-11-12

Last updated by the study team

2026-02-25

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Between the ages of 18-85
• Traumatic brain injury more than a year prior to study participation
• Word finding difficulty since the brain injury
• Fluent in speaking and reading English.

You may not qualify if…

• Implanted/electronic device, such as a pacemaker, metallic cranial or intracranial implant (e.g., ventriculoperitoneal shunt), or a neurostimulator (e.g., vagus nerve stimulator, spinal stimulator, deep brain stimulator, etc.).
• Skull defects
• History of a psychological or neurological disorder, including, dementia of any type, epilepsy or other seizure disorders, post-traumatic stress disorder, brain tumor, present drug abuse, stroke, blood vessel abnormalities in the brain, Parkinson's disease, Huntington's disease, or multiple sclerosis.
• Inability to give informed consent
• Military personnel or Veteran
• Currently pregnant
• Not fluent English speaker

Where it is running

• The University of Texas at Dallas — Richardson, Texas, United States

Full record on ClinicalTrials.gov

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