Ultrasonographic Patterns and Pathological Correlation in the Diagnosis of Subcutaneous Nodules

Recruiting now · Not applicable

Conditions studied: Nodules, Ultrasonography, Panniculitis

In brief

The objective of this study is to explore the role of ultrasonography (non-invasive imaging device) in the diagnosis of subcutaneous nodules (mass/bumb underneath the skin). Patients who presented with subcutaneous nodules and was indicated for diagnostic skin biopsies were recruited. Prior to skin biopsies (not part of the study's intervention), ultrasonography(intervention) was used to examine the characteristics of the nodules. The ultrasonographic findings are then compared to the pathological results to explore the role of ultrasonography in differentiating each disease or group of diseases that presented with skin nodules.

Key facts

Study ID

NCT06838988

Run by

Mahidol University

People needed

100

Starts

2025-02-24

Expected to finish

2026-01-01

Last updated by the study team

2025-05-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged 18 years and older who presented with subcutaneous nodules
• Indicated for pathological examination for disease diagnosis.
• Patients with subcutaneous nodules located in areas where a tissue sample can be taken down to the fat layer.
• Patients who agree to participate in the project by signing the consent form.

You may not qualify if…

• Presence of inflammation or other tumors that can mimic panniculitis, such as painful lipomas, cellulitis, and leg interstitial edema.
• Patients with diseases that significantly alter the structure of the skin or subcutaneous tissue, such as scleroderma or severe edema.
• A history of previous treatments in the area of the subcutaneous mass (e.g., surgery, radiation therapy, or high-dose steroid treatment) that may interfere with ultrasound results.
• Patients with lesions on the head or mucous membranes of the body.
• Pregnant or breastfeeding patients.
• Presence of wounds or open sores in the area to be examined with ultrasound.
• A history of coagulopathy (blood clotting disorders).
• Patients with metal implants in the area of interest that may interfere with ultrasound imaging.
• Participants who refuse or withdraw from the study.

Where it is running

• Ramathibodi Hospital — Bangkok, Ratchathewi, Thailand (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.