COMPARISON BETWEEN EFFICACY OF NOREPINEPHRINE AND PHENYLEPHRINE BOLUSES for PREVENTION OF SPINAL ANAESTHESIA INDUCED HYPOTENSION IN OBSTETRICAL PATIENTS UNDERGOING EMERGENCY CESAREAN SECTION-A Double Blind Randomized Controlled Trial
Recruiting now · Not applicable
Conditions studied: Spinal Anesthesia Induced Hypotension
In brief
The goal of this clinical trial is to learn if norepinephrine is more effective than phenylephrine for prevention of spinal anesthesia induced hypotension. The main questions it aims to answer are: Does norepinephrine lower the incidence of spinal anesthesia induced hypotension in emergency obstetrical patients? We will compare effectiveness of norepinephrine and phenylephrine for the prevention of spinal anesthesia induced hypotension. Participants will: Be administered prophylactic boluses of both drugs right after spinal anesthesia induction and maternal hemodynamic parameters and neonatal APGAR scores will be recorded
Key facts
- Study ID
- NCT06836986
- Run by
- Dow University of Health Sciences
- People needed
- 124
- Starts
- 2024-12-31
- Expected to finish
- 2025-03-31
- Last updated by the study team
- 2025-02-20
Who can join
Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- American society of anesthesiologists II and III patients
- Age 18-40years
- Gestational age 32 weeks and above
You may not qualify if…
- Patients with hypertensive disorders of pregnancy having baseline systolic blood pressure greater than 160 mmHg and diastolic blood pressure greater than 99 mmHg.
- Baseline mean arterial pressure less than 70 mmHg.
- Antepartum hemorrhage/intraoperative blood loss greater than 1000ml
- history indicative of cardiovascular or neurological disease.
- known fetal abnormality.
- Patients taking serotonin reuptake inhibitor, Tricyclic antidepressants,monoamine oxidase inhibitors.
- Maternal situations requiring immediate administration of general anesthesia
Where it is running
- Dr Ruth km pfau civil hospital karachi Dow University of health sciences, department of anesthesiology — Karachi, Sindh, Pakistan (enrolling)
Full record on ClinicalTrials.gov
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