Development of Attentional Biases for Affective Cues in Infants of Mothers With Depression

Recruiting now · Not applicable

Conditions studied: Depression - Major Depressive Disorder

In brief

The goal of this study is to examine attentional biases for facial displays of emotion as a mechanism of risk in infants of mothers with postpartum major depression, and the potential role of infant arousal in the development of these attentional biases.

Key facts

Study ID

NCT06835855

Run by

Binghamton University

People needed

225

Starts

2024-11-14

Expected to finish

2029-07-01

Last updated by the study team

2025-02-20

Who can join

Age: 1 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The high-risk group (n = 150) will consist of women with at least one episode of MDD since their baby's birth.
• To qualify for the low-risk group (n = 75), women cannot have a history of any depressive disorder or any current psychiatric diagnoses.
• Infants will be required to be singleton children born full-term (> 37 weeks) and normal weight (> 2,500 grams) with no birth complications or health problems to avoid medical complications contributing to infants' attention, reactivity, and regulation measures.
• The two groups will be matched on demographic factors (e.g., age, race/ethnicity, income).

You may not qualify if…

• Additional exclusion criteria are diagnoses of alcohol or substance use disorders currently or at any point during pregnancy, or lifetime history of bipolar or psychotic disorders.

Where it is running

• Binghamton University — Binghamton, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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