Assessing Concentrations of Methadone and Its Metabolites

Enrolling by invitation

Conditions studied: Opioid Use Disorder, Pain

In brief

An observational proof of concept method comparison study. Comparing Liquid Chromatography -Mass Spectroscopy to a new Quantitative Lateral Flow Immunoassay with an Optical Reader.

Key facts

Study ID

NCT06835582

Run by

Cari Health Inc.

People needed

20

Starts

2025-03-17

Expected to finish

2026-02-01

Last updated by the study team

2025-02-19

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-70. A prescription for methadone at a dose of 10mg or more for at least 7 days. Participants may be taking the methadone to treat an OUD or for pain. Taking methadone as prescribed during the last 4 days before consent to participate in the study.
• Has been prescribed at least 1 day of take-home doses.
• Exclusion criteria for methadone group includes:
• Age <18 or >70. A condition preventing or complicating blood collection. Conditions may include dermatological (skin) condition, bleeding diathesis, immunodeficiency, recent blood donation, anemia, end stage renal disease, liver cirrhosis, cancer, congestive heart failure, bleeding diathesis, tuberculosis (TB), active severe depression (e.g., suicidal ideation), or mania symptoms.
• Tattoo or piercing close to sampling area. Under a conservatorship.

Where it is running

• Synergy — Lemon Grove, California, United States

Full record on ClinicalTrials.gov

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