Study on the Mechanism of Cognitive Impairment in Patients with Moyamoya Disease

Recruiting now

Conditions studied: Moyamoya Disease

In brief

The purpose of this study is to comprehensively evaluate the risk factors for cognitive decline in patients with moyamoya disease, identify imaging target areas associated with cognitive damage in the brain, and explore the changes in brain structure and functional networks resulting from cerebral revascularization, as well as their relationship with cognitive improvement.

Key facts

Study ID

NCT06832839

Run by

Beijing Tiantan Hospital

People needed

360

Starts

2024-12-16

Expected to finish

2027-12-31

Last updated by the study team

2025-02-18

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The admission cerebral angiography (DSA) examination fulfills the diagnostic criteria for moyamoya disease.
• Please sign the informed consent form.
• Participants must be between 18 and 60 years of age.

You may not qualify if…

• Patients with concurrent atherosclerosis, autoimmune diseases, meningitis, brain tumors, Down syndrome, craniocerebral trauma, prior radioactive head irradiation, or hyperthyroidism, which may result in secondary cerebrovascular lesions leading to symptoms associated with smoke syndrome.
• Individuals younger than 18 years or older than 60 years.
• Those with contraindications for magnetic resonance imaging.
• Patients who are unable to complete cognitive brain assessments

Where it is running

• Beijing Tiantan Hospital — Beijing, China, China (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.