Modified Diagnosis and Treatment of Neonatal Hemolysis With ETCOc in sNH

Recruiting now · Early Phase 1

Conditions studied: Neonatal Hyperbilirubinemia

In brief

The goal of this clinical trial is to learn if modified diagnosis and treatment (MDT) of neonatal hemolysis (a common cause to newborn jaundice) incorporated with ETCOc measurement (a non-invasive measurement of exhaled gas) works to prevent brain damage in newborns with severe hyperbilirubinemia (sNH). It will also learn about the. occurrence of cranial MRI in the study participants. The main questions it aims to answer are: * Does MDT lower the possibilities participants have brain damage before the age of one? * How many times of abnormalities in cranial MRI is detected before the age of one? Researchers will compare MDT to a control (a current management) to see if MDT works to prevent brain damage in newborns with sHN. Participants will: * Take MDT or a control method in the management of sNH * Assess if there's brain damage before discharge and at the year of one * Record how many times of abnormalities in cranial MRI is detected before the age of one

Key facts

Study ID
NCT06832800
Run by
Women's Hospital School Of Medicine Zhejiang University
People needed
250
Starts
2025-07-21
Expected to finish
2027-12-31
Last updated by the study team
2026-01-20

Who can join

Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

Where it is running

Full record on ClinicalTrials.gov

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