The Effects of Diet on Small Non-coding RNA i Sperm Cells and the Possible Effects on Reproductive Success: Diet Intervention Effects on Sperm

Recruiting now · Not applicable

Conditions studied: Changes in sncRNA in Sperm, Male Fertility, RNA Profile

In brief

In this study, patients with infertility treated with IVF at the Center of Reproductive Medicine in Linköping, Sweden, will receive recipes and food according to Nordic dietary guidelines. The purpose is to investigate whether a short diet intervention is sufficient to improve sperm quality and shift the small non-coding RNA profile. In our previous study sperm showed rapid response to diet.

Key facts

Study ID

NCT06831292

Run by

Ostergotland County Council, Sweden

People needed

100

Starts

2024-12-26

Expected to finish

2027-12-01

Last updated by the study team

2026-05-05

Who can join

Age: 23 and older, up to 56. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Male (biological) partner in infertile couple, scheduled for first IVF treatment
• Mature sperm cells in semen
• Able to speak and read Swedish
• Omnivore
• Will refrain from nicotine and alcohol during intervention
• Sperm sampled provided no more than 3 weeks before intervention start

You may not qualify if…

• Former or present malignant disease
• Former radiotherapy in pelvic area
• Former chemotherapy
• Known genetic/chromosomal disorder
• Food allergy

Where it is running

• University Hospital — Linköping, Östergötland County, Sweden (enrolling)

Full record on ClinicalTrials.gov

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