Aquagenic Wrinkling Prediction

Recruiting now

Conditions studied: Aquagenic Wrinkling of Palms, Carrier State

In brief

The goal of this observational study is to determine whether an aquagenic wrinkling procedure (i.e., soaking hands in a water bath for up to 20 minutes) can be used as a screening tool for cystic fibrosis carrier status. Participants will complete one visit where they will undergo an aquagenic wrinkling procedure to see how their hands respond.

Key facts

Study ID

NCT06831110

Run by

University of Iowa

People needed

2000

Starts

2025-03-06

Expected to finish

2026-12-01

Last updated by the study team

2026-06-04

Who can join

Age: 18 and older, up to 24. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Interested in participating in other CF Carrier-related research studies.

You may not qualify if…

• CF patient status
• Unable to speak English
• Unable to provide written informed consent
• Prisoner status
• An open wound on either hand
• A tattoo on either hand
• Missing any portion of either hand
• Diagnosis of Diabetes
• Diagnosis of Hyperhidrosis
• Diagnosis of Raynaud's Disease
• Diagnosis of Atopic Dermatitis
• Regularly taking ACE inhibitors or angiotensin receptor blockers

Where it is running

• University of Iowa — Iowa City, Iowa, United States (enrolling)

Full record on ClinicalTrials.gov

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