The Effect of Uterine Entry In Fetoscopic Laser Photocoagulation for Twin-To-Twin Transfusion Syndrome

Recruiting now · Not applicable

Conditions studied: Twin to Twin Transfusion

In brief

The purpose of this study is to evaluate whether the entry technique surgeons use to get inside the uterus to perform fetoscopic laser photocoagulation for twin-to-twin transfusion syndrome has an effect on the rates of chorioamniotic membrane separation.

Key facts

Study ID

NCT06829901

Run by

Baylor College of Medicine

People needed

216

Starts

2025-03-14

Expected to finish

2030-12-01

Last updated by the study team

2026-03-04

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Patients who are eligible and elect to undergo fetoscopic selective laser photocoagulation for complicated monochorionic-diamniotic twin pregnancies with twin-to-twin transfusion syndrome.
• Patients will be between 16 0/7 weeks and 26 0/7 weeks gestational age.

You may not qualify if…

• Patients who do not elect to undergo fetoscopic laser photocoagulation for the treatment of complicated monochorionic-diamniotic twin pregnancies with twin-to-twin transfusion syndrome.
• Triplets and higher order multiple gestations.
• Patients who are less than 16 0/7 weeks or greater than 26 0/7 weeks gestational age.
• Patients with a short cervix (less than 1.5 cm).
• Patients with a known subchorionic hemorrhage.

Where it is running

• Texas Children's Hospital - Pavilion for Women — Houston, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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