Influence of Sarcopenia on the Course of the Diseases

Recruiting now

Conditions studied: Liver Cirrhosis, Cancer, Cachexia, Sarcopenia, Mechanical Ventilation

In brief

Frailty is a geriatric syndrome that primarily affects older patients, but also patients with severe illnesses. It is particularly common among oncology patients, but also among patients with gastrointestinal diseases such as liver cirrhosis or pancreatitis. Sarcopenia, a form of frailty, is defined as a loss of muscle quantity, quality and function. Currently, complex methods such as CT or bioimpedance measurement are available. However, simpler techniques such as ultrasound-based measurement could be alternatives, but still require further validation. In addition, serological muscle markers could support and simplify diagnostics. The aim of this project is to be able to estimate the prognosis of patients at an early stage by measuring sarcopenia using ultrasound and biomarkers.

Key facts

Study ID

NCT06829290

Run by

Universitatsmedizin Mainz - 1. Medizinische Klinik

People needed

200

Starts

2024-10-01

Expected to finish

2028-10-01

Last updated by the study team

2025-02-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• oncological patient in the field of gastrointestinal tumors
• patients with liver cirrhosis
• patients attending the intensive care unit

You may not qualify if…

• patients incapable of consenting
• patients with congenital muscle diseases

Where it is running

• Universitatsmedizin Mainz — Mainz, Rhineland-Palatinate, Germany (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.