Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension.
Recruiting now · Not applicable
Conditions studied: Hypertension, Vascular Function, Fitness Testing, Metabolism Changes
In brief
This is a prospective, monocentric, randomized controlled trial to investigate the effect of anti-hypertensive treatment and/or individualized exercise training intervention on blood pressure and vascular health. Furthermore the investigators want to decipher mechanisms, which contribute to vascular health by analyzing changes in metabolism and cell function in relation to vascular reaction.
Key facts
- Study ID
- NCT06823570
- Run by
- Heinrich-Heine University, Duesseldorf
- People needed
- 60
- Starts
- 2025-04-01
- Expected to finish
- 2028-12-31
- Last updated by the study team
- 2025-03-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- systolic hypertension grade I-II (BP values >140 mmHg to <180 mmHg) without anti-hypertensive medication treatment
You may not qualify if…
- no written informed consent
- age <18 years
- isolated diastolic hypertension
- medical contraindications for the exercise treatment (for example orthopedic problems or an abnormal ECG during the cardio respiratory exercise test)
- chronic eye diseases on both eyes (for example macular degeneration or glaucoma) or high intraocular pressure (>20 mmHg)
Where it is running
- Universitätsklinik Düsseldorf — Düsseldorf, Düsseldorf, Germany (enrolling)
Full record on ClinicalTrials.gov
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