The Canadian Lung Outcomes in Users of Vaping Devices Study
Recruiting now
Conditions studied: Small Airways Diseases, Vaping, Vaping Related Disorder, Vaping Teens, Vaping Behavior
In brief
Vaping is increasingly popular with both adolescent and adult Canadians, but the long-term health impacts remain unknown. We believe that the tools we currently have to detect lung disease in people who vape may be insufficient and propose new ways to find lung injuries that may impact them over the course of their lives. These include exercise testing, new imaging techniques, and new breathing tests that will demonstrate how vaping may harm their lungs. We will use these tools in both adolescent and adult Canadians to give Canadians who vape important information on the consequences of vaping.
Key facts
- Study ID
- NCT06819969
- Run by
- University of British Columbia
- People needed
- 500
- Starts
- 2025-07-25
- Expected to finish
- 2029-12-31
- Last updated by the study team
- 2026-03-30
Who can join
Age: 12 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Adolescent arm:
- Aged ≥12 and <19 years old
- Either 1) use neither combustible cigarettes nor e-cigarettes or 2) use e-cigarettes exclusively
- Adult arm:
- Aged ≥19 years old
- Fall into one of the following categories: 1) use neither combustible cigarettes nor e-cigarettes; 2) use combustible cigarettes exclusively, never using e-cigarettes; 3) use e-cigarettes exclusively, never using combustible cigarettes; or 4) use both combustible cigarettes and e-cigarettes currently
You may not qualify if…
- Adolescent arm:
- Contraindication to pulmonary function testing and cardiopulmonary exercise testing
- Have smoked combustible cannabis within the last month and/or have a combustible cannabis smoking history of >1 joint-year
- Have smoked combustible cigarettes within the last 6 months
- Have a physician-diagnosed chronic lung disease (such as asthma, cystic fibrosis, or bronchopulmonary dysplasia)
- Inability to provide written informed consent
- Adult arm:
- Contraindication to pulmonary function testing and cardiopulmonary exercise testing
- Have smoked combustible cannabis within the last month and/or have a combustible cannabis smoking history of >1 joint-year
- Currently undergoing treatment for lung cancer
- Inability to provide written informed consent
- No limitations will be placed on the type of e-liquids used by participants; e.g., e-cigarette users of nicotine, tetrahydrocannabinol, and cannabidiol will be all enrolled.
Where it is running
- University of Ottawa (The Ottawa Hospital General Campus) — Ottawa, Ontario, Canada (enrolling)
- BC Children's Hospital Research Institute — Vancouver, British Columbia, Canada (enrolling)
- University of Alberta (Clinical Sciences Building) — Edmonton, Alberta, Canada (enrolling)
- St. Paul's Hospital — Vancouver, British Columbia, Canada (enrolling)
- BC Cancer Agency — Vancouver, British Columbia, Canada (enrolling)
- Université de Sherbrooke — Sherbrooke, Quebec, Canada
- McMaster University (Research Institute of St. Joe's Hamilton) — Hamilton, Ontario, Canada
- University of Toronto (The Hospital for Sick Children) — Toronto, Ontario, Canada
Full record on ClinicalTrials.gov
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