Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients

Recruiting now · Not applicable

Conditions studied: Leprosy, Mycobacterium Leprae Infection

In brief

Mycobacterium leprae is a slow-growing bacillus that causes leprosy. the infection may take two to ten years to incubate. While the exact mechanism of infection transmission is unknown, direct bacillus absorption through the nasal or respiratory mucosa and aerosolized nasal secretions are the most common theories. The bacteria is subsequently transported by the bloodstream to the peripheral nerves, where it can result in tissue damage from painless burns and ulcers as well as irreparable nerve damage that results in a loss of protective feeling.

Key facts

Study ID

NCT06819449

Run by

South Valley University

People needed

50

Starts

2024-12-20

Expected to finish

2025-12-20

Last updated by the study team

2025-02-11

Who can join

Age: 5 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients of both sexes with positive slit skin smear for m.leprae .

You may not qualify if…

• Contraindications to Multi drug therapy :
• Patients with hypersensitivity to sulfa .
• Patients with hypersensitivity to clofazimine or rifampcin.
• pregnant or lactating women.

Where it is running

• Qina University hospital, South Valley University Hospital — Qina, Egypt (enrolling)

Full record on ClinicalTrials.gov

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