Examining Interactions Between PALS and Caregivers

Recruiting now · Not applicable

Conditions studied: Amyotrophic Lateral Sclerosis (ALS)

In brief

The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and their caregivers. The question is, What are the effects of communicative interaction on verbal communication in people with ALS when they interact with their caregivers and does this change over time? Participants will read words and sentences while they are interacting with their caregivers.

Key facts

Study ID

NCT06819124

Run by

Penn State University

People needed

152

Starts

2025-01-22

Expected to finish

2029-02-28

Last updated by the study team

2026-04-06

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Speakers with amyotrophic lateral sclerosis (ALS) (PALS-people with ALS)
• diagnosis of ALS following the revised EL Escorial criteria
• no history of other neurological conditions (e.g., stroke)
• no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA)
• detectable speech disturbance according to the ALS Functional Rating Scale-Revised (ALSFRS-R)
• the ability to produce single words
• being a native speaker of American English (AE).
• Caregivers
• being a caregiver of a participant with ALS
• being a native speaker of American English (AE).

You may not qualify if…

• None - if volunteer meets the inclusion criteria, then they will be enrolled

Where it is running

• Speech Core, Pennsylvania State University — University Park, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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