Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery

Recruiting now · Not applicable

Conditions studied: Delayed Onset Muscle Soreness

In brief

Both BFR and intermittent pneumatic compression are purported to decrease symptoms associated with exercise induced muscle damage (EIMD) that cause delayed onset muscle soreness (DOMS). Blood flow restriction relies on applying pressurized cuffs to the most proximal portion of the limb. Another form of recovery often relied upon is pneumatic compression. The mechanism by which pneumatic compression works is similar to that of a massage, whereby the device progressively increases the pressure on a portion of the limb before releasing and moving further up the limb.The purpose of this study is determine whether BFR or pneumatic compression can be used to decreased DOMS which may indicate enhanced recovery.

Key facts

Study ID

NCT06815367

Run by

University of Southern California

People needed

33

Starts

2024-01-15

Expected to finish

2026-05-01

Last updated by the study team

2026-03-30

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18-30 years of age
• Recreationally active population
• Women should be on a form of hormonal contraception.
• No current musculoskeletal injuries or pathologies
• Must answer "yes" to all PAR-Q questions.

You may not qualify if…

• Individuals that routinely train trail running
• Discomfort when running
• Deep vein thrombosis
• Blood clots
• Cancerous lesions
• Sensory or mental impairment
• Unstable fractures
• Acute pulmonary edema
• Acute thrombophlebitis
• Acute congestive cardiac failure
• Acute infections
• Episodes of pulmonary embolism
• Wounds, lesions, infection, or tumors
• Bone fractures or dislocations
• Increased venous and lymphatic return
• Answers "no" to any of the PAR-Q screening questions

Where it is running

• University of Southern California — Los Angeles, California, United States (enrolling)

Full record on ClinicalTrials.gov

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